ReproSil 50 SEC is a normal-phase silica column specifically optimized for size exclusion chromatography (SEC) in the molecular weight range of 500 – 10,000 Da. The carefully controlled pore structure of the silica ensures efficient size-based separation of small to medium biomolecules, providing reproducible results with minimal secondary interactions. With its high mechanical stability and optimized pore distribution, ReproSil 50 SEC delivers sharp peak shapes and reliable fractionation, making it suitable for both analytical and preparative applications in biochemistry, pharmaceuticals, and polymer research.
ReproSil 50 SEC combines optimized silica pore design with robust stability – the dependable choice for accurate SEC separations in the 500–10,000 Da range.
Normal-phase silica designed for size exclusion chromatography (SEC)
Optimized pore structure for 500 – 10,000 Da molecular weight range
Minimal secondary interactions for accurate size-based separations
High mechanical stability and reproducibility
Suitable for analytical and preparative workflows
Manufactured and QC-tested by Dr. Maisch HPLC GmbH
Available in 5 µm and 10 µm particle sizes
Size exclusion analysis of peptides and small proteins
Separation of oligosaccharides and nucleotides
Molecular weight determination of biopolymers and synthetic polymers
Fractionation of complex mixtures in pharmaceutical and biochemical research
| Particle Sizes |
|
|---|---|
| Pore Size | 50 Å |
| Phase/Modification | Diol |
| Particle Type | |
| Separation Mode | |
| USP Code | |
| Endcapping | No |
| pH Range | 2 to 8 |
| Phase | Material Number |
|---|---|
| ReproSil 50 SEC, 5 µm | r05.sec. |
| ReproSil 50 SEC, 10 µm | r00.sec. |