ReproSil 5000 SEC is a silica-based HPLC column designed for size exclusion chromatography (SEC) in the molecular weight range of 150,000 – 1,250,000 Da. With its large pore structure, the column is optimized for the separation and characterization of very large biomolecules and high-molecular-weight polymers. The stationary phase ensures accurate size-based fractionation with minimal secondary interactions, while providing excellent mechanical stability and reproducibility. This makes ReproSil 5000 SEC the ideal choice for analytical and preparative SEC applications in biotechnology, polymer science, and pharmaceutical research.
ReproSil 5000 SEC combines robust silica performance with large-pore SEC selectivity – the reliable choice for high-precision separations of very large biomolecules and polymers in the 150,000–1,250,000 Da range.
Silica-based stationary phase for size exclusion chromatography
Molecular weight separation range: 150,000 – 1,250,000 Da
Optimized for very large biomolecules and synthetic polymers
High reproducibility, robust performance, and long column lifetime
Suitable for analytical and preparative workflows
Manufactured and QC-tested by Dr. Maisch HPLC GmbH
Available in 5 µm
Separation and analysis of very large proteins and protein complexes
Characterization of nucleic acids and biopolymers
Molecular weight distribution studies of synthetic high polymers
Biotechnological and pharmaceutical research involving macromolecules
| Particle Size |
|
|---|---|
| Pore Size | 800 Å |
| Surface Area | 60 m²/g |
| Phase/Modification | PEG |
| Particle Type | |
| Separation Mode | |
| USP Code | |
| Endcapping | No |
| Carbonload | 5 % |
| pH Range | 2 to 8 |
| Phase | Material Number |
|---|---|
| ReproSil 5000 SEC, 5 µm | r55.sec. |