ReproSil Star 100 C8

Balanced Retention C8 Column for High-Efficiency Reversed-Phase HPLC

ReproSil Star 100 C8 is a high-purity silica-based HPLC column with a C8 bonded phase, developed for demanding pharmaceutical and biotechnical separations. The shorter alkyl chains of the C8 modification provide moderate hydrophobic retention and faster elution compared to C18 phases, making this column ideal for analytes with medium polarity or for methods requiring reduced run times.

The specially treated ReproSil Star silica ensures high mechanical and chemical stability, sharp peak shapes, and reproducible retention even under challenging gradient or temperature conditions. This phase is particularly suitable for routine pharmaceutical analysis, impurity profiling, and biotechnical applications involving peptides and biomolecules.

ReproSil Star 100 C8 combines optimized silica performance with controlled hydrophobicity – the dependable choice for efficient pharmaceutical and biotechnical HPLC separations.

Direct alternative to Oyster C8 (former from Merck-India).

Key Features:

  • Fully porous, ultra-pure silica with 100 Å pore size

  • C8 bonding – USP L7 classification

  • Balanced hydrophobic retention for faster separations

  • Excellent reproducibility, resolution, and peak shapes

  • Manufactured and QC-tested by Dr. Maisch HPLC GmbH

Typical Applications:

  • Pharmaceutical drug substance and impurity analysis

  • Environmental testing for organic contaminants

  • Food and beverage quality control

  • Method development requiring moderate retention

Specifications

Request Product
Particle Sizes
  • 3 µm
  • 5 µm
Pore Size 100 Å
Surface Area 450 m²/g
Phase/Modification C8
Particle Type
Separation Mode
USP Code
Endcapping Yes
Carbonload 15 %
pH Range 2 to 8

Material Numbers

Phase Material Number
ReproSil Star 100 C8, 3 µm star3.8e.
ReproSil Star 100 C8, 5 µm star5.8e.
ReproSil Star 100 ODS-3

Any questions?
We are here to help you.

info@dr-maisch.com +49 7073 5035 7

Follow us