ReproSil Star 100 ODS-3

High-Efficiency C18 Column for Reproducible Reversed-Phase HPLC

ReproSil Star 100 ODS-3 is a silica-based HPLC column with a C18 bonded phase, specifically developed for high-performance separations in pharmaceutical and biotechnical applications. The ODS-3 bonding provides strong hydrophobic retention and broad applicability, making it ideal for a wide range of compounds from small drug molecules to peptides and biomolecules.

The high-purity silica used in the ReproSil Star series offers excellent mechanical and chemical stability, while advanced endcapping ensures minimal silanol activity and outstanding peak symmetry. This phase delivers reliable retention, high efficiency, and reproducible results even under demanding gradient or temperature conditions.

ReproSil Star 100 ODS-3 combines high hydrophobic selectivity with outstanding reproducibility – the reliable choice for precise pharmaceutical and biotechnical HPLC separations.

Direct alternative to Oyster ODS-3 (former from Merck-India).

Key Features:

  • Fully porous, ultra-pure silica with 100 Å pore size

  • ODS-3 C18 bonding – USP L1 classification

  • Strong hydrophobic retention with excellent selectivity

  • High efficiency, reproducibility, and peak shape performance

  • Manufactured and QC-tested by Dr. Maisch HPLC GmbH

Typical Applications:

  • Pharmaceutical drug substance, impurity, and stability testing

  • Environmental monitoring of hydrophobic pollutants

  • Food and beverage quality control

  • Method development for reversed-phase separations

Specifications

Request Product
Particle Sizes
  • 3 µm
  • 5 µm
Pore Size 100 Å
Surface Area 450 m²/g
Phase/Modification C18
Particle Type
Separation Mode
USP Code
Endcapping Yes
Carbonload 17 %
pH Range 2 to 8

Material Numbers

Phase Material Number
ReproSil Star 100 ODS-3, 3 µm star3.93.
ReproSil Star 100 ODS-3, 5 µm star5.93.
ReproSil Star 100 C8 ReproSil Star 300 SB-C18

Any questions?
We are here to help you.

info@dr-maisch.com +49 7073 5035 7

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