ReproSil Star 300 SB-C18

Wide-Pore C18 Column for Large Biomolecule Reversed-Phase Separations

ReproSil Star 300 SB-C18 from Dr. Maisch HPLC GmbH is a high-purity silica-based HPLC column with a 300 Å pore size and a stable-bond octadecyl stationary phase. The wide-pore structure ensures optimal accessibility and efficient mass transfer for high-molecular-weight analytes such as proteins, enzymes, antibodies, and peptides. The stable-bond C18 chemistry offers strong hydrophobic retention combined with excellent durability, enabling reproducible separations even under rigorous gradient conditions.

ReproSil Star 300 SB-C18 columns from Dr. Maisch HPLC GmbH combine wide-pore accessibility with strong hydrophobic selectivity – the optimal choice for high-resolution large biomolecule chromatography.

Attractive alternative to Zorbax 300 SB-C18 (Agilent Technologies).

Key Features:

  • Fully porous, ultra-pure silica with 300 Å pore size

  • Stable-bond C18 – USP L1 classification

  • Strong hydrophobic retention for large biomolecules

  • Excellent resolution, peak symmetry, and reproducibility

  • Manufactured and QC-tested by Dr. Maisch HPLC GmbH

Typical Applications:

  • Protein and peptide separations in proteomics and biopharma

  • Biopharmaceutical QC and characterization of therapeutic proteins

  • Gradient HPLC of hydrophobic biomolecules

  • Preparative separations of large analytes

Specifications

Request Product
Particle Size
  • 5 µm
Pore Size 300 Å
Phase/Modification C18
Particle Type
Separation Mode
USP Code
pH Range 2 to 8

Material Number

Phase Material Number
ReproSil Star 300 SB-C18, 5 µm star35.sb9.
ReproSil Star 100 ODS-3 ReproSil Star NH2

Any questions?
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info@dr-maisch.com +49 7073 5035 7

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