ReproSil Star Phenyl-Ether

Aromatic Selectivity Column for Polar and Non-Polar Compound Separations

ReproSil Star Phenyl-Ether is a silica-based HPLC column with a phenyl-ether bonded phase, developed for demanding pharmaceutical and biotechnical applications. The phenyl-ether functionality combines π–π interactions of the aromatic ring with additional dipole and hydrogen-bonding contributions from the ether linkage. This dual-interaction mechanism offers enhanced selectivity for aromatic, polar, and moderately hydrophobic compounds.

Built on high-purity, mechanically stable silica, ReproSil Star Phenyl-Ether delivers sharp peak shapes, excellent reproducibility, and reliable retention under a wide range of chromatographic conditions. It is particularly suited for analytes where subtle differences in aromatic substitution or polarity must be resolved with precision.

ReproSil Star Phenyl-Ether combines aromatic selectivity with polar interaction capability – the dependable choice for precise and reproducible HPLC separations in pharmaceutical and biotechnical analysis.

Key Features:

  • Fully porous, ultra-pure silica with phenyl-ether bonding

  • Combines aromatic π–π interactions with polar selectivity

  • Suitable for polar and non-polar analytes in one method

  • High efficiency, resolution, and reproducibility

  • Manufactured and QC-tested by Dr. Maisch HPLC GmbH

Typical Applications:

  • Separation of aromatic pharmaceuticals and metabolites

  • Analysis of phenolic compounds and natural products

  • Complex mixture separations requiring dual-mode selectivity

  • Method development with orthogonal selectivity to C18 phases

Specifications

Request Product
Particle Sizes
  • 1.8 µm
  • 3 µm
  • 5 µm
Pore Size 120 Å
Phase/Modification Phenyl-Ether
Particle Type
Separation Mode
USP Code
Endcapping Yes
Carbonload 8 %
pH Range 2 to 8

Applications

Material Numbers

Phase Material Number
ReproSil Star Phenyl-Ether, 1.8 µm star18.pet
ReproSil Star Phenyl-Ether, 3 µm star3.pet.
ReproSil Star Phenyl-Ether, 5 µm star5.pet.
ReproSil Star NH2 ReproSil Star RP18-e

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info@dr-maisch.com +49 7073 5035 7

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