ReproSil Star RP18-e

Endcapped C18 Column for High-Efficiency Reversed-Phase HPLC

ReproSil Star RP18-e is a silica-based HPLC column featuring an endcapped C18 bonded phase, specifically developed for high-performance separations in pharmaceutical and biotechnical applications. The endcapping minimizes residual silanol activity, resulting in improved peak symmetry, reproducible retention, and excellent performance for basic, polar, and hydrophobic analytes alike.

The high-purity silica matrix of the ReproSil Star series ensures mechanical and chemical stability, delivering consistent results even under demanding gradient or pH conditions. ReproSil Star RP18-e provides strong hydrophobic retention, high efficiency, and broad applicability, making it a versatile choice for method development, quality control, and research workflows.

ReproSil Star RP18-e combines robust silica technology with endcapped C18 selectivity – the reliable choice for high-efficiency and reproducible HPLC separations in pharmaceutical and biotechnical analysis.

Attractive Alternative to Purospher Star RP18e (Merck).

Key Features:

  • Fully porous, ultra-pure silica with 120 Å pore size

  • Endcapped C18 bonding – USP L1 classification

  • Strong hydrophobic retention with excellent peak shapes

  • Reduced silanol activity for better performance with basic analytes

  • Manufactured and QC-tested by Dr. Maisch HPLC GmbH

Typical Applications:

  • Pharmaceutical drug substance and impurity profiling

  • Environmental monitoring of hydrophobic pollutants

  • Food and beverage quality control

  • Method development for robust reversed-phase separations

Specifications

Request Product
Particle Sizes
  • 2 µm
  • 3 µm
  • 5 µm
  • 10 µm
Pore Size 120 Å
Surface Area 300 m²/g
Phase/Modification C18
Particle Type
Separation Mode
USP Code
Endcapping Yes
Carbonload 17 %
pH Range 2 to 8

Material Numbers

Phase Material Number
ReproSil Star RP18-e, 2 µm star2.9e.
ReproSil Star RP18-e, 3 µm star3.9e.
ReproSil Star RP18-e, 5 µm star5.9e.
ReproSil Star RP18-e, 10 µm star0.9e.
ReproSil Star Phenyl-Ether ReproSil Star SAX

Any questions?
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info@dr-maisch.com +49 7073 5035 7

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