ReproSil Star SAX-2

Endcapped Strong Anion Exchange Phase for Pharmaceutical and Biotechnical Applications

ReproSil Star SAX-2 is an endcapped, silica-based HPLC column featuring strong anion exchange functionality. As an enhanced version of ReproSil Star SAX, this phase combines the powerful ion-exchange capacity of quaternary ammonium groups with an additional endcapping step that minimizes residual silanol activity. The result is improved peak symmetry, reduced secondary interactions, and highly reproducible retention for negatively charged analytes.

Engineered on high-purity, mechanically stable silica, ReproSil Star SAX-2 delivers reliable performance even under varying pH and buffer conditions. This makes it ideal for demanding applications in pharmaceutical, biochemical, and biotechnological separations, where precision and robustness are essential.

ReproSil Star SAX-2 unites strong anion exchange performance with the benefits of endcapping – the advanced choice for precise, stable, and reproducible anion exchange separations in HPLC.

Key Features:

  • Endcapped silica-based stationary phase with strong anion exchange (SAX) functionality

  • Improved peak shapes and reduced secondary interactions compared to non-endcapped SAX

  • Strong retention and high selectivity for negatively charged analytes

  • Excellent reproducibility under diverse chromatographic conditions

  • Suitable for analytical and preparative workflows

  • Manufactured and QC-tested by Dr. Maisch HPLC GmbH

Typical Applications:

  • Separation of organic acids, nucleotides, and other anionic biomolecules

  • Pharmaceutical analysis of ionizable compounds and impurities

  • Biotechnological research requiring high selectivity and reproducibility

  • Method development in ion exchange and mixed-mode chromatography

Specifications

Request Product
Particle Size
  • 5 µm
Pore Size 200 Å
Surface Area 160 m²/g
Phase/Modification Propyl-SAX
Particle Type
Separation Mode
USP Code
Endcapping Yes
Carbonload 7 %
pH Range 2 to 10

Material Number

Phase Material Number
ReproSil Star SAX-2, 5 µm star5.sax2.
ReproSil Star SAX ReproSil Star SAX-3

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info@dr-maisch.com +49 7073 5035 7

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