ReproSil Star SAX-3

Advanced Strong Anion Exchange Column for Enhanced Acidic Compound Separations

ReproSil Star SAX-3 is a silica-based HPLC column with strong anion exchange functionality and an enlarged pore size of 300 Å, developed for the separation of large biomolecules such as proteins, peptides, and nucleic acids. Compared to the standard ReproSil Star SAX, the wider pore structure of SAX-3 provides improved mass transfer and accessibility for high-molecular-weight analytes, ensuring efficient ion-exchange interactions and sharp peak shapes.

The stationary phase is built on high-purity, mechanically stable silica with quaternary ammonium groups, offering robust retention, excellent reproducibility, and long column lifetime under various buffer and gradient conditions. ReproSil Star SAX-3 is ideally suited for biotechnological and pharmaceutical applications requiring selective and reproducible anion exchange chromatography of macromolecules.

ReproSil Star SAX-3 extends the proven performance of the SAX phase to large biomolecules – the reliable choice for high-resolution anion exchange separations using a 300 Å pore silica matrix.

Key Features:

  • Silica-based stationary phase with quaternary ammonium (SAX) functionality

  • 300 Å pore size for improved separation of large biomolecules

  • Strong anion exchange capacity with high reproducibility

  • Excellent performance under varying pH and buffer conditions

  • Designed for analytical and preparative biotechnological workflows

  • Manufactured and QC-tested by Dr. Maisch HPLC GmbH

Typical Applications:

  • Separation and purification of proteins, peptides, and nucleic acids

  • Analysis of large biomolecules in pharmaceutical and biotechnological research

  • Method development for ion exchange chromatography of macromolecules

  • Quality control and process monitoring in biopharmaceutical production

Specifications

Request Product
Particle Size
  • 5 µm
Pore Size 300 Å
Phase/Modification Propyl-SAX
Particle Type
Separation Mode
USP Code
pH Range 2 to 8

Material Number

Phase Material Number
ReproSil Star SAX-3, 5 µm star5.sax2.
ReproSil Star SAX-2 ReproSil Star SB-C8

Any questions?
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info@dr-maisch.com +49 7073 5035 7

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