ReproSil Gold 100 C18-XBD

Extra Base-Deactivated C18 Column for LC-MS Optimized Separations

ReproSil Gold 100 C18-XBD is a premium reversed-phase HPLC column from Dr. Maisch HPLC GmbH, packed with ultra-pure spherical silica bonded with octadecyl ligands and featuring eXtra Base Deactivation (XBD) technology. This surface modification eliminates virtually all residual silanol activity, ensuring outstanding peak symmetry, minimal tailing, and high reproducibility, even for strongly basic or polar analytes. With its strong hydrophobic retention and superior deactivation, ReproSil Gold 100 C18-XBD is perfectly suited for LC-MS workflows, delivering ultra-low bleed, high sensitivity, and robust performance in pharmaceutical, bioanalytical, and environmental applications.

ReproSil Gold 100 C18-XBD from Dr. Maisch HPLC GmbH combines premium C18 retention with advanced base deactivation – the ideal choice for laboratories demanding precision, robustness, and maximum LC-MS compatibility.

Key Features:

  • C18 reversed-phase with eXtra Base Deactivation (XBD) – USP L1

  • Optimized for LC-MS with ultra-low bleed and maximum sensitivity

  • Excellent peak shape for basic, polar, and ionizable analytes

  • 100 Å pore size for small molecules and peptides

  • Manufactured and QC-tested by Dr. Maisch HPLC GmbH

Typical Applications:

  • LC-MS analysis of drug substances, metabolites, and impurities

  • Bioanalytical and pharmaceutical QC requiring high reproducibility

  • Gradient separations with superior peak symmetry

  • Method development for sensitive or regulated LC-MS workflows

Specifications

Request Product
Particle Sizes
  • 1.8 µm
  • 2 µm
  • 3 µm
  • 5 µm
  • 10 µm
Pore Size 100 Å
Surface Area 350 m²/g
Phase/Modification C18
Particle Type
Separation Mode
USP Code
Endcapping Yes
Carbonload 16.5 %
pH Range 2 to 8

Material Numbers

Phase Material Number
ReproSil Gold 100 C18-XBD, 1.8 µm g118.9x.
ReproSil Gold 100 C18-XBD, 2 µm g12.9x.
ReproSil Gold 100 C18-XBD, 3 µm g13.9x.
ReproSil Gold 100 C18-XBD, 5 µm g15.9x.
ReproSil Gold 100 C18-XBD, 10 µm g10.9x.
ReproSil Gold 100 C8-XBD

Any questions?
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info@dr-maisch.com +49 7073 5035 7

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