ReproSil Gold 100 C8-XBD is a high-purity reversed-phase HPLC column from Dr. Maisch HPLC GmbH, based on ultra-pure spherical silica bonded with octyl ligands and featuring eXtra Base Deactivation (XBD) technology. This advanced surface treatment eliminates residual silanol activity, resulting in exceptional peak symmetry and minimal tailing, even for strongly basic analytes. The moderate hydrophobic retention of the C8 phase, combined with the XBD deactivation, makes this column perfectly suited for LC-MS workflows, ensuring low bleed, high sensitivity, and robust reproducibility. It is an excellent choice for pharmaceutical, bioanalytical, and high-throughput laboratories requiring both speed and precision.
ReproSil Gold 100 C8-XBD from Dr. Maisch HPLC GmbH delivers outstanding LC-MS compatibility and base-deactivated performance – the ideal column for laboratories requiring precision, robustness, and low-bleed separations.
C8 reversed-phase with extra Base Deactivation – USP L7
Optimized for LC-MS with ultra-low bleed and high sensitivity
Excellent peak shape for basic and polar compounds
100 Å pore size for small molecules and peptides
Manufactured and QC-tested by Dr. Maisch HPLC GmbH
Available from 1.8 µm to 10 µm particle sizes
LC-MS analysis of pharmaceuticals, drug metabolites, and impurities
Bioanalytical workflows requiring high sensitivity and reproducibility
Fast separations of moderately hydrophobic analytes
Method development for regulated environments and routine QC
| Particle Sizes |
|
|---|---|
| Pore Size | 100 Å |
| Surface Area | 350 m²/g |
| Phase/Modification | C8 |
| Particle Type | |
| Separation Mode | |
| USP Code | |
| Endcapping | Yes |
| Carbonload | 10.5 % |
| pH Range | 2 to 8 |
| Phase | Material Number |
|---|---|
| ReproSil Gold 100 C8-XBD, 1.8 µm | g118.8x. |
| ReproSil Gold 100 C8-XBD, 2 µm | g12.8x. |
| ReproSil Gold 100 C8-XBD, 3 µm | g13.8x. |
| ReproSil Gold 100 C8-XBD, 5 µm | g15.8x. |
| ReproSil Gold 100 C8-XBD, 10 µm | g10.8x. |