ReproSil-XR 300 C4 from Dr. Maisch HPLC GmbH is a high-purity silica-based wide-pore HPLC column with a 300 Å pore size and a butyl bonded phase. The short alkyl chain provides lower hydrophobic retention than C18 or C8, allowing milder elution conditions that help preserve the structure and bioactivity of proteins, peptides, and other sensitive large biomolecules. The wide-pore design ensures excellent accessibility and efficient mass transfer, making this column ideal for analytical and preparative separations in biopharmaceutical and proteomics workflows.
ReproSil-XR 300 C4 columns from Dr. Maisch HPLC GmbH combine wide-pore accessibility with gentle separation conditions – the ideal choice for high-performance biomolecule chromatography.
Fully porous, ultra-pure silica with 300 Å pore size
C4 bonding – USP L26 classification
Lower hydrophobic retention for gentle biomolecule analysis
Excellent reproducibility, resolution, and peak symmetry
Manufactured and QC-tested by Dr. Maisch HPLC GmbH
Available in 3 µm, 5 µm, and 10 µm particle sizes
Protein and peptide separations under mild conditions
Biopharmaceutical QC and characterization of therapeutic proteins
Gradient HPLC of hydrophobic biomolecules
Preparative purification of sensitive analytes
| Particle Sizes |
|
|---|---|
| Pore Size | 300 Å |
| Surface Area | 100 m²/g |
| Phase/Modification | C4 |
| Particle Type | |
| Separation Mode | |
| USP Code | |
| Endcapping | Yes |
| Carbonload | 3 % |
| pH Range | 2 to 8 |
| Phase | Material Number |
|---|---|
| ReproSil-XR 300 C4, 3 µm | rx33.4e. |
| ReproSil-XR 300 C4, 5 µm | rx35.4e. |
| ReproSil-XR 300 C4, 10 µm | rx30.4e. |