ReproSil-XR 300 SCX

Wide-Pore Strong Cation Exchange Column for Large Biomolecule Separations

ReproSil-XR 300 SCX from Dr. Maisch HPLC GmbH is a high-purity silica-based wide-pore HPLC column with a 300 Å pore size and a strong cation exchange (SCX) bonded phase based on sulfonic acid functional groups. This stationary phase provides strong ionic retention for positively charged biomolecules, ensuring high resolution, sharp peak shapes, and excellent reproducibility. The wide-pore structure allows optimal accessibility and efficient mass transfer for high-molecular-weight analytes such as proteins, enzymes, and peptides, making it particularly suited for proteomics and biopharmaceutical applications.

ReproSil-XR 300 SCX columns from Dr. Maisch HPLC GmbH combine wide-pore accessibility with strong ionic selectivity – the optimal choice for high-resolution large biomolecule chromatography.

Key Features:

  • Fully porous, ultra-pure silica with 300 Å pore size

  • Strong cation exchange (SCX) phase with sulfonic acid groups

  • High selectivity for basic proteins, peptides, and other biomolecules

  • Excellent reproducibility, resolution, and peak symmetry

  • Manufactured and QC-tested by Dr. Maisch HPLC GmbH

  • Available in 3 µm, and 5 µm particle sizes

Typical Applications:

  • Protein and peptide separations via strong cation exchange

  • Biopharmaceutical QC and charge variant analysis

  • Fractionation of protein isoforms in proteomics

  • Preparative purification of basic biomolecules

Specifications

Request Product
Particle Sizes
  • 3 µm
  • 5 µm
Pore Size 300 Å
Surface Area 100 m²/g
Phase/Modification SCX
Particle Type
Separation Mode
USP Codes
Endcapping No
Carbonload 4 %
pH Range 2 to 8

Material Numbers

Phase Material Number
ReproSil-XR 300 SCX, 3 µm rx33.scx.
ReproSil-XR 300 SCX, 5 µm rx35.scx.
ReproSil-XR 300 C18

Any questions?
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info@dr-maisch.com +49 7073 5035 7

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