ReproSil 100 C18-AB

Acid-Base Stable C18 Column for Robust Reversed-Phase HPLC

ReproSil 100 C18-AB from Dr. Maisch HPLC GmbH is a fully porous, high-purity silica HPLC column with a 100 Å pore size and an acid-base stable octadecyl bonded phase. Engineered for long-term stability across a wide pH range, this column maintains excellent peak shapes and reproducible retention times even under acidic or basic mobile phase conditions. Its versatile selectivity and chemical robustness make it ideal for method development, stability-indicating assays, and regulated pharmaceutical analysis where durability and reproducibility are critical.

ReproSil 100 C18-AB columns from Dr. Maisch HPLC GmbH deliver pH-stable, high-performance reversed-phase chromatography – the ideal choice for robust and reproducible HPLC workflows.

Key Features:

  • Fully porous, ultra-pure silica with 100 Å pore size

  • Acid-base stable C18 bonding – USP L1 classification

  • Wide pH tolerance for challenging separations

  • Excellent peak symmetry and retention stability

  • Manufactured and QC-tested by Dr. Maisch HPLC GmbH

  • Available in 5 µm

Typical Applications:

  • Stability-indicating pharmaceutical methods

  • Gradient and isocratic separations under varied pH conditions

  • Impurity profiling and method validation

  • Routine QC in pharmaceutical, chemical, and food analysis

Specifications

Request Product
Particle Size
  • 5 µm
Pore Size 100 Å
Surface Area 280 m²/g
Phase/Modification C18
Particle Type
Separation Mode
USP Code
Endcapping Yes
Carbonload 18 %
pH Range 2 to 8

Material Number

Phase Material Number
ReproSil 100 C18-AB, 5 µm r15.9b.
ReproSil 100 C18 ReproSil 100 C18-TDE

Any questions?
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info@dr-maisch.com +49 7073 5035 7

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