ReproSil 100 Diol from Dr. Maisch HPLC GmbH is a fully porous, high-purity silica HPLC column with a 100 Å pore size and a diol-functionalized bonded phase. This stationary phase provides moderate polarity and hydrogen bonding capability, making it ideal for normal-phase chromatography, hydrophilic interaction chromatography (HILIC), and size exclusion chromatography (SEC) of biomolecules. Its controlled polarity reduces strong adsorption of polar analytes while maintaining good retention and reproducibility, enabling reliable separation of carbohydrates, polar pharmaceuticals, and biomolecules.
ReproSil 100 Diol columns from Dr. Maisch HPLC GmbH deliver versatile polar selectivity – the reliable choice for normal-phase, HILIC, and SEC separations in HPLC.
Fully porous, ultra-pure silica with 100 Å pore size
Diol functional groups for polar interactions
Suitable for normal-phase, HILIC, and SEC applications
Reduced strong adsorption for improved peak shapes
Manufactured and QC-tested by Dr. Maisch HPLC GmbH
Available in 5 µm and 10 µm particle sizes
Carbohydrate and sugar alcohol analysis
Polar pharmaceutical compound separations
Glycoprotein and biomolecule SEC
Method development requiring controlled polar selectivity
| Particle Sizes |
|
|---|---|
| Pore Size | 100 Å |
| Surface Area | 280 m²/g |
| Phase/Modification | Diol |
| Particle Type | |
| Separation Modes | |
| USP Code | |
| Endcapping | No |
| Carbonload | 3 % |
| pH Range | 2 to 8 |
| Phase | Material Number |
|---|---|
| ReproSil 100 Diol, 5 µm | r15.d6. |
| ReproSil 100 Diol, 10 µm | r10.d6. |