ReproSil 100 SCX

Strong Cation Exchange Column for Selective Separation of Basic Analytes

ReproSil 100 SCX from Dr. Maisch HPLC GmbH is a fully porous, high-purity silica HPLC column with a 100 Å pore size and a strong cation exchange bonded phase based on sulfonic acid functional groups. This chemistry provides strong ionic interactions for the retention and separation of positively charged analytes, including basic pharmaceuticals, amines, and peptides. The column delivers high selectivity, excellent peak symmetry, and reproducible retention in both isocratic and gradient ion-exchange methods.

ReproSil 100 SCX columns from Dr. Maisch HPLC GmbH provide robust and selective cation exchange chromatography – ideal for high-performance separation of basic and positively charged analytes.

Key Features:

  • Fully porous, ultra-pure silica with 100 Å pore size

  • Strong cation exchange functionality (sulfonic acid groups)

  • High selectivity and resolution for basic analytes

  • Compatible with isocratic and gradient elution

  • Manufactured and QC-tested by Dr. Maisch HPLC GmbH

  • Available in 3 µm, 5 µm, and 10 µm particle sizes

Typical Applications:

  • Separation of basic drugs and active pharmaceutical ingredients

  • Analysis of peptides and positively charged biomolecules

  • Ion-exchange method development in pharmaceutical and bioanalysis

  • QC of cationic compounds in chemical manufacturing

Specifications

Request Product
Particle Sizes
  • 3 µm
  • 5 µm
  • 10 µm
Pore Size 100 Å
Surface Area 210 m²/g
Phase/Modification Sulfopropyl
Particle Type
Separation Mode
USP Code
Endcapping No
pH Range 2 to 8

Applications

Material Numbers

Phase Material Number
ReproSil 100 SCX, 3 µm r13.sc.
ReproSil 100 SCX, 5 µm r15.sc.
ReproSil 100 SCX, 10 µm r10.sc.
ReproSil 100 RP18-NE ReproSil 100 Si

Any questions?
We are here to help you.

info@dr-maisch.com +49 7073 5035 7

Follow us