ReproSil Amid-C12 from Dr. Maisch HPLC GmbH is a fully porous, high-purity silica HPLC column with a polar-embedded amid-C12 bonded phase. This unique stationary phase combines hydrophobic retention from the C12 alkyl chain with polar interactions from the embedded amide group, offering improved retention and selectivity for polar analytes and ionizable compounds. The polar-embedded design enhances wetting properties, allowing stable operation in 100% aqueous mobile phases without phase collapse, while providing excellent peak symmetry even for basic analytes.
ReproSil Amid-C12 columns from Dr. Maisch HPLC GmbH deliver enhanced selectivity and aqueous stability – the ideal choice for polar compound chromatography in reversed-phase HPLC.
Fully porous, ultra-pure silica with polar-embedded amid-C12 bonding
Balanced hydrophobic and polar selectivity
Stable in 100% aqueous eluents – no phase collapse
Excellent peak shapes for polar and basic compounds
Manufactured and QC-tested by Dr. Maisch HPLC GmbH
Available from 1.5 µm to 10 µm particle sizes
Retention of polar pharmaceuticals and metabolites
100% aqueous reversed-phase separations
Analysis of ionizable and hydrophilic analytes
Method development requiring mixed-mode selectivity
| Particle Sizes |
|
|---|---|
| Pore Size | 120 Å |
| Surface Area | 170 m²/g |
| Phase/Modification | Amid-C12 |
| Particle Type | |
| Separation Modes | |
| USP Code | |
| Endcapping | No |
| Carbonload | 9 % |
| pH Range | 2 to 8 |
| Phase | Material Number |
|---|---|
| ReproSil Amid-C12, 1.5 µm | r215.a12. |
| ReproSil Amid-C12, 3 µm | r23.a12. |
| ReproSil Amid-C12, 5 µm | r25.a12. |
| ReproSil Amid-C12, 10 µm | r20.a12. |