ReproSil Amid-C16

Polar-Embedded C16 Column for Enhanced Selectivity and Peak Shape

ReproSil Amid-C16 from Dr. Maisch HPLC GmbH is a high-purity silica-based HPLC column with a polar-embedded amidic C16 bonded phase. This stationary phase combines hydrophobic retention from the C16 alkyl chains with polar interactions from the embedded amide groups, resulting in improved peak shapes for basic compounds and enhanced retention of polar analytes. The amidic functionality also increases phase stability under acidic and basic conditions, making the column well-suited for robust, reproducible separations in pharmaceutical, environmental, and food analysis.

ReproSil Amid-C16 columns from Dr. Maisch HPLC GmbH deliver balanced hydrophobic and polar retention with excellent peak shapes – the ideal choice for complex reversed-phase HPLC separations.

Key Features:

  • Fully porous, ultra-pure silica with amidic C16 bonded phase

  • Polar-embedded design for dual hydrophobic and polar interactions

  • Improved peak symmetry for basic compounds

  • Enhanced retention of polar analytes in reversed-phase mode

  • Manufactured and QC-tested by Dr. Maisch HPLC GmbH

  • Available in 5 µm

Typical Applications:

  • Pharmaceutical drug and metabolite analysis

  • Separation of polar and basic compounds in one run

  • Method development requiring orthogonal selectivity

  • Food and environmental contaminant testing

Specifications

Request Product
Particle Size
  • 5 µm
Pore Size 100 Å
Surface Area 280 m²/g
Phase/Modification Amid-C16
Particle Type
Separation Modes
USP Code
Endcapping Yes
pH Range 2 to 8

Material Number

Phase Material Number
ReproSil Amid-C16, 5 µm r15.a16.
ReproSil Amid-C12 ReproSil Amid-C18

Any questions?
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info@dr-maisch.com +49 7073 5035 7

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