ReproSil Amid-C18-e from Dr. Maisch HPLC GmbH is a fully porous, high-purity silica HPLC column with a polar-embedded amid-C18 bonded phase and endcapping for further reduction of residual silanol activity. This combination delivers strong hydrophobic retention with enhanced polar selectivity, while ensuring excellent peak symmetry for basic and polar analytes. The polar-embedded design allows stable operation in 100% aqueous mobile phases without phase collapse, making it ideal for highly hydrophilic compounds and mixed-mode selectivity in method development.
ReproSil Amid-C18-e columns from Dr. Maisch HPLC GmbH deliver superior peak symmetry, aqueous stability, and polar selectivity – the optimal choice for challenging reversed-phase HPLC separations.
Fully porous, ultra-pure silica with polar-embedded amid-C18 bonding
Endcapped for minimized silanol interactions and improved peak shape
Stable in 100% aqueous eluents – no phase collapse
Balanced hydrophobic and polar retention for diverse analytes
Manufactured and QC-tested by Dr. Maisch HPLC GmbH
Available in 5 µm
Separation of polar pharmaceuticals and metabolites
LC-MS compatible aqueous-phase methods
Analysis of basic drugs and aromatic systems
Method development with mixed-mode selectivity
| Particle Size |
|
|---|---|
| Pore Size | 100 Å |
| Surface Area | 280 m²/g |
| Phase/Modification | C18 |
| Particle Type | |
| Separation Modes | |
| USP Code | |
| Endcapping | Yes |
| pH Range | 2 to 8 |
| Phase | Material Number |
|---|---|
| ReproSil Amid-C18-e, 5 µm | r15.a18e. |