ReproSil Amid-C18 ABZ

Polar-Embedded C18 Column for Maximum Selectivity and pH Stability

ReproSil Amid-C18 ABZ from Dr. Maisch HPLC GmbH is a fully porous, high-purity silica HPLC column with a polar-embedded amid-C18 bonded phase and an ABZ (Acid-Base stable) surface modification. This advanced bonding technology combines strong hydrophobic retention from the C18 chain with polar interactions from the embedded amide group, delivering enhanced selectivity for polar, basic, and aromatic analytes while maintaining stability across a wide pH range. The ABZ treatment increases resistance to hydrolysis under acidic and basic conditions, extending column lifetime and ensuring consistent performance in demanding analytical environments.

ReproSil Amid-C18 ABZ columns from Dr. Maisch HPLC GmbH deliver maximum selectivity, aqueous stability, and pH robustness – the ideal solution for challenging reversed-phase HPLC applications.

Key Features:

  • Fully porous, ultra-pure silica with polar-embedded amid-C18 bonding

  • Acid-base stable chemistry for extended pH range operation

  • Maintains retention in 100% aqueous mobile phases

  • Excellent peak shapes for polar and basic compounds

  • Manufactured and QC-tested by Dr. Maisch HPLC GmbH

  • Available in 3 µm and 5 µm particle sizes

Typical Applications:

  • Wide-pH pharmaceutical separations and stability-indicating assays

  • Polar and ionizable compound analysis under aqueous conditions

  • LC-MS compatible reversed-phase separations

  • Method development requiring robust, mixed-mode selectivity

Specifications

Request Product
Particle Sizes
  • 3 µm
  • 5 µm
Pore Size 200 Å
Surface Area 200 m²/g
Phase/Modification C18
Particle Type
Separation Modes
USP Codes
Endcapping No
Carbonload 12.5 %
pH Range 2 to 8

Material Numbers

Phase Material Number
ReproSil Amid-C18 ABZ, 3 µm r23.ace.
ReproSil Amid-C18 ABZ, 5 µm r25.ace.
ReproSil Amid-C18 ReproSil Amid-C18-e

Any questions?
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info@dr-maisch.com +49 7073 5035 7

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