ReproSil 200 C18-Aqua

Wide-Pore Aqueous-Compatible C18 Column for Polar Biomolecules

ReproSil 200 C18-Aqua from Dr. Maisch HPLC GmbH is a fully porous, high-purity silica HPLC column with a 200 Å pore size and an aqueous-compatible C18 bonded phase. Designed to maintain hydrophobic retention in highly aqueous mobile phases, this column is ideal for polar peptides, proteins, and hydrophilic biomolecules that require wide-pore accessibility. The phase is engineered to prevent phase collapse in 100% aqueous eluents, ensuring stable retention, sharp peak shapes, and high reproducibility for both small and large polar analytes.

ReproSil 200 C18-Aqua columns from Dr. Maisch HPLC GmbH deliver aqueous stability with wide-pore selectivity – the perfect choice for polar biomolecule chromatography in HPLC.

Key Features:

  • Fully porous, ultra-pure silica with 200 Å pore size

  • Aqueous-compatible C18 bonding – USP L1 classification

  • Stable in 100% aqueous mobile phases

  • Optimized for polar peptides, proteins, and biomolecules

  • Manufactured and QC-tested by Dr. Maisch HPLC GmbH

  • Available in 5 µm

Typical Applications:

  • Polar peptide and protein separations in proteomics

  • Hydrophilic biomolecule analysis in biopharma QC

  • LC-MS compatible reversed-phase methods

  • Method development requiring aqueous stability

Specifications

Request Product
Particle Size
  • 5 µm
Pore Size 200 Å
Surface Area 150 m²/g
Phase/Modification C18
Particle Type
Separation Mode
USP Codes
Endcapping Yes
pH Range 2 to 8

Material Number

Phase Material Number
ReproSil 200 C18-Aqua, 5 µm r25.9aq.
ReproSil 200 C18 ReproSil 200 Diol

Any questions?
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info@dr-maisch.com +49 7073 5035 7

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