ReproSil 200 Diol

Wide-Pore Diol Column for SEC, Normal-Phase, and HILIC Separations

ReproSil 200 Diol from Dr. Maisch HPLC GmbH is a fully porous, high-purity silica HPLC column with a 200 Å pore size and a diol-functionalized bonded phase. This stationary phase provides moderate polarity and hydrogen bonding capability, making it ideal for size exclusion chromatography (SEC) of proteins, glycoproteins, and other biomolecules, as well as for normal-phase and HILIC separations. The wide-pore design ensures efficient mass transfer and optimal accessibility for larger molecules, while the diol surface reduces irreversible adsorption of polar analytes.

ReproSil 200 Diol columns from Dr. Maisch HPLC GmbH deliver versatile wide-pore chromatography – the ideal choice for SEC, normal-phase, and HILIC biomolecule separations.

Key Features:

  • Fully porous, ultra-pure silica with 200 Å pore size

  • Diol functionalization for polar interaction chromatography

  • Suitable for SEC, normal-phase, and HILIC applications

  • Reduced irreversible adsorption for improved recovery

  • Manufactured and QC-tested by Dr. Maisch HPLC GmbH

  • Available in 5 µm

Typical Applications:

  • SEC of proteins, glycoproteins, and biomacromolecules

  • HILIC separations of polar compounds and biomolecules

  • Normal-phase separations in biopharma and natural product analysis

  • Method development requiring gentle polar interactions

Specifications

Request Product
Particle Size
  • 5 µm
Pore Size 200 Å
Surface Area 150 m²/g
Phase/Modification Diol
Particle Type
Separation Modes
USP Code
Endcapping No
pH Range 2 to 8

Material Number

Phase Material Number
ReproSil 200 Diol, 5 µm r25.d6.
ReproSil 200 C18-Aqua ReproSil 200 Si

Any questions?
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info@dr-maisch.com +49 7073 5035 7

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