ReproSil 200 C4-Aqua from Dr. Maisch HPLC GmbH is a fully porous, high-purity silica HPLC column with a 200 Å pore size and an aqueous-compatible butyl bonded phase. The shorter alkyl chain offers reduced hydrophobic retention compared to C18 or C8 phases, enabling gentler elution for proteins, peptides, and other biomolecules while preserving their structural integrity. Engineered to prevent phase collapse in 100% aqueous mobile phases, this column ensures stable retention, excellent peak symmetry, and high reproducibility for hydrophilic and amphiphilic biomolecules.
ReproSil 200 C4-Aqua columns from Dr. Maisch HPLC GmbH combine gentle C4 selectivity with aqueous stability – the ideal choice for sensitive protein and peptide chromatography in HPLC.
Fully porous, ultra-pure silica with 200 Å pore size
Aqueous-compatible C4 bonding – USP L26 classification
Lower hydrophobic retention for biomolecule-friendly separations
Stable in 100% aqueous mobile phases
Manufactured and QC-tested by Dr. Maisch HPLC GmbH
Available in 5 µm
Protein and peptide separations under mild elution conditions
LC-MS compatible aqueous reversed-phase workflows
Biopharmaceutical QC and proteomics research
Method development for hydrophilic biomolecules
| Particle Size |
|
|---|---|
| Pore Size | 200 Å |
| Surface Area | 150 m²/g |
| Phase/Modification | C4 |
| Particle Type | |
| Separation Mode | |
| USP Codes | |
| Endcapping | Yes |
| pH Range | 2 to 8 |
| Phase | Material Number |
|---|---|
| ReproSil 200 C4-Aqua, 5 µm | r25.4aq. |