ReproSil 200 C8-Aqua

Wide-Pore Aqueous-Compatible C8 Column for Polar Peptides and Proteins

ReproSil 200 C8-Aqua from Dr. Maisch HPLC GmbH is a fully porous, high-purity silica HPLC column with a 200 Å pore size and an aqueous-compatible octyl bonded phase. Offering moderate hydrophobic retention, this phase is ideal for polar peptides, proteins, and hydrophilic biomolecules, providing faster elution than C18 phases while maintaining excellent resolution. The aqueous-compatible bonding prevents phase collapse in 100% aqueous eluents, ensuring stable retention, sharp peak shapes, and high reproducibility, even for highly polar analytes.

ReproSil 200 C8-Aqua columns from Dr. Maisch HPLC GmbH deliver balanced retention and aqueous stability – the perfect choice for polar biomolecule chromatography in HPLC.

Key Features:

  • Fully porous, ultra-pure silica with 200 Å pore size

  • Aqueous-compatible C8 bonding – USP L7 classification

  • Moderate retention for faster analysis of biomolecules

  • Stable in 100% aqueous mobile phases

  • Manufactured and QC-tested by Dr. Maisch HPLC GmbH

  • Available in 5 µm

Typical Applications:

  • Polar peptide and protein chromatography

  • LC-MS compatible reversed-phase analysis

  • Biopharmaceutical QC and proteomics workflows

  • Method development for hydrophilic biomolecules

Specifications

Request Product
Particle Size
  • 5 µm
Pore Size 200 Å
Surface Area 150 m²/g
Phase/Modification C8
Particle Type
Separation Mode
USP Codes
Endcapping Yes
pH Range 2 to 8

Material Number

Phase Material Number
ReproSil 200 C8-Aqua, 5 µm r25.8 aq.
ReproSil 200 C4-Aqua ReproSil 200 C18

Any questions?
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info@dr-maisch.com +49 7073 5035 7

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