ReproSil 200 Si

Wide-Pore Unmodified Silica for Normal-Phase Chromatography of Biomolecules

ReproSil 200 Si from Dr. Maisch HPLC GmbH is a fully porous, high-purity silica HPLC column with a 200 Å pore size and an unmodified silica surface. The wide-pore structure provides excellent accessibility for proteins, peptides, and other large biomolecules, making it ideal for normal-phase chromatography, adsorption chromatography, and SFC (supercritical fluid chromatography). Its high surface area and controlled silanol activity ensure reproducible retention, high resolution, and compatibility with both aqueous and organic mobile phases.

ReproSil 200 Si columns from Dr. Maisch HPLC GmbH deliver reliable, reproducible wide-pore performance – the preferred choice for normal-phase and SFC biomolecule separations.

Key Features:

  • Fully porous, ultra-pure silica with 200 Å pore size

  • Unmodified silica for strong polar interactions

  • Optimized for large biomolecules in normal-phase chromatography

  • Suitable for SFC and adsorption-based separations

  • Manufactured and QC-tested by Dr. Maisch HPLC GmbH

  • Available in 5 µm

Typical Applications:

  • Normal-phase separation of proteins, peptides, and glycoproteins

  • SFC analysis of biopolymers and natural products

  • Adsorption chromatography of polar biomolecules

  • Method development requiring wide-pore bare silica

Specifications

Request Product
Particle Size
  • 5 µm
Pore Size 200 Å
Surface Area 150 m²/g
Phase/Modification Si
Particle Type
Separation Modes
USP Code
Endcapping No
Carbonload 0 %
pH Range 2 to 8

Material Number

Phase Material Number
ReproSil 200 Si, 5 µm r25.06.
ReproSil 200 Diol ReproSil-PAH-Plus

Any questions?
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info@dr-maisch.com +49 7073 5035 7

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