Reprospher 100 2-EP is a reversed-phase HPLC column from Dr. Maisch HPLC GmbH, packed with ultra-pure, fully porous spherical silica (100 Å pore size) functionalized with 2-ethylpyridine ligands. This unique phase offers both hydrophobic and π-basic interactions, making it particularly effective for the separation of basic, polar, and aromatic analytes with improved peak symmetry and reduced tailing compared to standard C18 materials. The basic character of the 2-ethylpyridine group suppresses residual silanol activity and enhances selectivity for compounds that are difficult to retain or resolve on conventional reversed-phase columns.
Reprospher 100 2-EP from Dr. Maisch HPLC GmbH offers reliable and distinct selectivity – ideal for laboratories working with difficult-to-separate basic and polar analytes in modern reversed-phase HPLC.
2-Ethylpyridine bonded reversed-phase silica – unique selectivity
Ideal for basic and aromatic compounds prone to tailing
Enhanced peak shape through π–π and weak base interactions
Fully porous, high-purity 100 Å spherical silica
Manufactured and QC-tested by Dr. Maisch HPLC GmbH
Separation of basic pharmaceuticals and drug impurities
Method development for challenging polar or aromatic analytes
Alternative selectivity for LC-MS-compatible workflows
Reversed-phase chromatography under neutral pH conditions
| Particle Sizes |
|
|---|---|
| Pore Size | 100 Å |
| Surface Area | 350 m²/g |
| Phase/Modification | 2-Ethylpyridin |
| Particle Type | |
| Separation Modes | |
| Endcapping | No |
| Carbonload | 8 % |
| pH Range | 2 to 8 |
| Phase | Material Number |
|---|---|
| Reprospher 100 2-EP, 5 µm | rs15.2ep. |
| Reprospher 100 2-EP, 10 µm | rs10.2ep. |