Reprospher 100 C12 is a reversed-phase HPLC column from Dr. Maisch HPLC GmbH, based on fully porous, high-purity silica with a 100 Å pore size and bonded with dodecyl ligands. This medium-chain phase provides a hydrophobicity level between C8 and C18, making it a versatile option for analytes that are either strongly retained on C18 or insufficiently separated on shorter-chain phases. It offers excellent peak shape, reproducibility, and retention stability, especially when moderate interaction strength is required to fine-tune separation conditions.
This C12 phase from Dr. Maisch HPLC GmbH delivers reliable, medium-strength reversed-phase performance – ideal for analytical tasks that require flexibility in retention and selectivity.
Dodecyl (C12) bonded reversed-phase phase – USP L32 classification
Fully porous silica with 100 Å pore size
Balanced retention for a wide range of hydrophobic analytes
High column efficiency and low silanol activity
Available in 4 µm and 5 µm particle sizes
Pharmaceutical compounds with intermediate hydrophobicity
Method development requiring adjusted retention strength
Analysis of drug substances, food components, and chemical intermediates
Reversed-phase LC-MS and UV workflows
| Particle Sizes |
|
|---|---|
| Pore Size | 100 Å |
| Surface Area | 350 m²/g |
| Phase/Modification | C12 |
| Particle Type | |
| Separation Mode | |
| USP Code | |
| Endcapping | Yes |
| Carbonload | 8 % |
| pH Range | 2 to 8 |
| Phase | Material Number |
|---|---|
| Reprospher 100 C12, 4 µm | rs14.12. |
| Reprospher 100 C12, 5 µm | rs15.12. |