Reprospher 100 C8-TN

Trifunctional C8 Reversed-Phase Column Without Endcapping for Polar Interaction and Robust Retention

Reprospher 100 C8-TN is a reversed-phase HPLC column from Dr. Maisch HPLC GmbH, packed with high-purity, fully porous spherical silica modified with trifunctionally bonded octyl groups and no endcapping (TN = trimodal, non-endcapped). This combination results in a stationary phase with moderate hydrophobic retention and increased silanol activity, enabling selective retention of polar and ionizable compounds through mixed-mode interactions. Ideal for analytical workflows that benefit from enhanced polar selectivity or controlled silanol interactions, Reprospher 100 C8-TN offers reliable performance in both isocratic and gradient reversed-phase separations.

Reprospher 100 C8-TN from Dr. Maisch HPLC GmbH offers distinct retention behavior and rugged reversed-phase performance – ideal for laboratories seeking alternative selectivity and enhanced polar interaction in HPLC.

Key Features:

  • Trifunctional C8 bonding on ultra-pure spherical silica

  • Not endcapped – allows for controlled silanol interaction

  • Moderate hydrophobic retention with additional polar selectivity

  • Robust bonding chemistry for improved phase stability

  • Manufactured and quality-controlled by Dr. Maisch HPLC GmbH

  • Available in 5 µm, 10 µm, and 15 µm particle sizes

Typical Applications:

  • Separation of polar and weakly retained analytes

  • Method development requiring mixed-mode interaction

  • Retention tuning for ionizable or basic compounds

  • Analytical reversed-phase HPLC with enhanced selectivity

Specifications

Request Product
Particle Sizes
  • 5 µm
  • 10 µm
  • 15 µm
Pore Size 100 Å
Surface Area 350 m²/g
Phase/Modification C8
Particle Type
Separation Mode
USP Code
Endcapping No
Carbonload 10 %
pH Range 2 to 8

Material Numbers

Phase Material Number
Reprospher 100 C8-TN, 5 µm rs15.8tn.
Reprospher 100 C8-TN, 10 µm rs10.8tn.
Reprospher 100 C8-TN, 15 µm rs115.8tn.
Reprospher 100 C8-NE Reprospher 100 C12

Any questions?
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info@dr-maisch.com +49 7073 5035 7

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