Reprospher 100 C18-Phenyl

Hybrid-Bonded Reversed-Phase Column with C18 and Phenyl Selectivity

Reprospher 100 C18-Phenyl is a reversed-phase HPLC column from Dr. Maisch HPLC GmbH, packed with ultra-pure, fully porous spherical silica, functionalized with a hybrid bonded phase that combines octadecyl chains and phenyl groups. This dual functionality enables strong hydrophobic retention via the C18 chains and enhanced selectivity for aromatic compounds through π–π interactions with the phenyl moiety. The result is a versatile reversed-phase column with broader selectivity than conventional C18 materials, particularly effective for analytes with aromatic, polar, or planar structures.

Reprospher 100 C18-Phenyl from Dr. Maisch HPLC GmbH offers powerful dual-mode reversed-phase performance – ideal for laboratories seeking enhanced resolution of aromatic, planar, and structurally similar analytes.

Key Features:

  • Hybrid C18 and phenyl bonded phase – USP L1 / L11

  • Strong hydrophobic retention and π–π selectivity

  • Enhanced separation of aromatic and structurally related analytes

  • Fully porous, high-purity 100 Å spherical silica

  • Manufactured and quality-controlled by Dr. Maisch HPLC GmbH

  • Available in 3 µm, 5 µm and 10 µm particle sizes

Typical Applications:

  • Separation of aromatic drugs and isomeric compounds

  • Impurity profiling in pharmaceutical development

  • Reversed-phase method development with extended selectivity

  • Gradient and isocratic HPLC of polar aromatic compounds

Specifications

Request Product
Particle Sizes
  • 3 µm
  • 5 µm
  • 10 µm
Pore Size 100 Å
Surface Area 350 m²/g
Phase/Modification C18-Phenyl
Particle Type
Separation Mode
USP Codes
Endcapping Yes
Carbonload 17 %
pH Range 2 to 8

Material Numbers

Phase Material Number
Reprospher 100 C18-Phenyl, 3 µm rs13.9ph.
Reprospher 100 C18-Phenyl, 5 µm rs15.9ph.
Reprospher 100 C18-Phenyl, 10 µm rs10.9ph.
Reprospher 100 C18-NE Reprospher 100 C18-TDE

Any questions?
We are here to help you.

info@dr-maisch.com +49 7073 5035 7

Follow us