Reprospher 100 C18-TN is a reversed-phase HPLC column from Dr. Maisch HPLC GmbH, packed with ultra-pure, fully porous spherical silica, modified with trifunctionally bonded octadecyl chains and deliberately not endcapped (TN = trimodal, non-endcapped). This phase offers strong hydrophobic retention through its C18 chains, while the absence of endcapping preserves residual silanol activity, allowing additional polar or ionic interactions. This unique surface design provides mixed-mode retention characteristics and is particularly valuable for analytes that benefit from silanol interactions, such as basic, polar, or ionizable compounds.
Reprospher 100 C18-TN from Dr. Maisch HPLC GmbH offers robust reversed-phase performance with enhanced polar selectivity – ideal for laboratories requiring controlled silanol activity and alternative retention behavior.
Trifunctional C18 bonding on ultra-pure spherical silica - USP L1
Not endcapped – active silanol sites for enhanced polar interaction
Strong hydrophobic retention with additional selectivity options
Suitable for gradient and isocratic reversed-phase separations
Manufactured and quality-controlled by Dr. Maisch HPLC GmbH
Available in 5 µm
Separation of polar or basic analytes with improved retention
Method development requiring silanol interaction
Mixed-mode retention strategies in reversed-phase HPLC
Profiling of compounds not well retained on standard C18 phases
| Particle Size |
|
|---|---|
| Pore Size | 100 Å |
| Surface Area | 350 m²/g |
| Phase/Modification | C18 |
| Particle Type | |
| Separation Mode | |
| USP Code | |
| Endcapping | No |
| Carbonload | 17 % |
| pH Range | 2 to 8 |
| Phase | Material Number |
|---|---|
| Reprospher 100 C18-TN, 5 µm | rs15.9tn. |