Reprospher 100 C6-TDE

Hexyl Reversed-Phase Column with Triple Deactivation for Basic Compound Analysis

Reprospher 100 C6-TDE is a high-performance reversed-phase HPLC column from Dr. Maisch HPLC GmbH, based on fully porous, high-purity silica with a 100 Å pore size. The stationary phase is bonded with hexyl ligands and features a triple deactivation surface treatment that significantly suppresses residual silanol activity. This results in excellent peak symmetry and retention stability, particularly for basic and tailing-prone analytes. With intermediate hydrophobicity between C4 and C8/C18 phases, Reprospher 100 C6-TDE provides balanced retention behavior, making it a valuable tool for method development and robust routine analysis.

Reprospher 100 C6-TDE from Dr. Maisch HPLC GmbH combines triple deactivation with balanced hydrophobicity – the ideal reversed-phase column for basic analytes and demanding method optimization.

Key Features:

  • Hexyl (C6) bonded reversed-phase phase with triple deactivation

  • Fully porous silica with 100 Å pore size

  • Enhanced peak shape for basic and ionizable compounds

  • Intermediate hydrophobicity – ideal for fine-tuning retention

Typical Applications:

  • Separation of basic drug substances and small molecules

  • Method development with tailored retention strength

  • Stability-indicating assays for tailing-prone compounds

  • Robust reversed-phase workflows in pharmaceutical QC and R&D

Specifications

Request Product
Particle Size
  • 5 µm
Pore Size 100 Å
Surface Area 350 m²/g
Phase/Modification C6
Particle Type
Separation Mode
USP Code
Endcapping Yes
Carbonload 8 %
pH Range 2 to 8

Material Number

Phase Material Number
Reprospher 100 C6-TDE, 5 µm rs15.6tde.
Reprospher 100 C4-DE Reprospher 100 C8

Any questions?
We are here to help you.

info@dr-maisch.com +49 7073 5035 7

Follow us