Reprospher 100 Diphenyl is a reversed-phase HPLC column from Dr. Maisch HPLC GmbH, based on high-purity, fully porous silica with a 100 Å pore size and bonded with diphenyl functional groups. The aromatic diphenyl ligand enhances π–π interactions and shape-selective retention, making this column ideal for separating planar molecules, aromatic isomers, and structurally similar compounds. Compared to C18 or phenyl phases, Reprospher 100 Diphenyl offers distinct selectivity and greater resolution for aromatic and electron-rich analytes, especially when analyzing pharmaceutical actives, natural products, or environmental samples.
Reprospher 100 Diphenyl from Dr. Maisch HPLC GmbH offers targeted aromatic interaction and selectivity – the ideal choice for separating π-conjugated and structurally related analytes in reversed-phase HPLC.
Diphenyl bonded reversed-phase phase – enhanced π–π selectivity
Fully porous silica with 100 Å pore size
High retention for aromatic and planar compounds
Orthogonal selectivity compared to C18 or phenyl phases
Available in 3 µm and 5 µm
Structural isomers, aromatic drug substances, and phenolic compounds
Natural product separations and metabolite profiling
Method development requiring alternative π-selectivity
Reversed-phase separations in pharmaceutical and environmental analysis
| Particle Sizes |
|
|---|---|
| Pore Size | 100 Å |
| Surface Area | 350 m²/g |
| Phase/Modification | Phe-Si-Phe |
| Particle Type | |
| Separation Mode | |
| USP Code | |
| Endcapping | Yes |
| pH Range | 2 to 8 |
| Phase | Material Number |
|---|---|
| Reprospher 100 Diphenyl, 3 µm | rs13.dpe. |
| Reprospher 100 Diphenyl, 5 µm | rs15.dpe. |