Reprospher 100 NH₂-DE is a polar HPLC column from Dr. Maisch HPLC GmbH, packed with fully porous, high-purity silica and bonded with aminopropyl (NH₂) ligands. The endcapping surface modification significantly reduces residual silanol activity, leading to improved peak shape and retention stability — especially in aqueous mobile phases and for basic or ionizable analytes. This column is ideal for normal-phase and HILIC separations of sugars, polyols, and polar drug substances, offering increased reproducibility and reduced peak tailing compared to conventional NH₂ phases.
Reprospher 100 NH₂-DE from Dr. Maisch HPLC GmbH delivers reliable, deactivated polar retention – the ideal solution for carbohydrate analysis and robust polar separations in normal-phase or HILIC mode.
Aminopropyl (NH₂) bonded phase with deactivated silanol surface – USP L8
Suitable for normal-phase, HILIC, and weak anion-exchange applications
Fully porous silica with 100 Å pore size
Improved peak symmetry and retention reproducibility
Available in 1.8 µm, 2 µm and 5 µm particle sizes
Separation of sugars, oligosaccharides, sugar alcohols
Organic acids and polar pharmaceutical excipients
HILIC and normal-phase method development
LC workflows with aqueous or organic-rich eluents
| Particle Sizes |
|
|---|---|
| Pore Size | 100 Å |
| Surface Area | 350 m²/g |
| Phase/Modification | NH2 |
| Particle Type | |
| Separation Modes | |
| USP Code | |
| Endcapping | Yes |
| Carbonload | 4 % |
| pH Range | 2 to 8 |
| Phase | Material Number |
|---|---|
| Reprospher 100 NH2-DE, 1.8 µm | rs118.ade. |
| Reprospher 100 NH2-DE, 2 µm | rs12.ade. |
| Reprospher 100 NH2-DE, 5 µm | rs15.ade. |