Reprospher 100 Phenyl is a reversed-phase HPLC column from Dr. Maisch HPLC GmbH, based on high-purity, fully porous silica with a 100 Å pore size and bonded with phenyl ligands. The π-electron system of the phenyl group enables π–π interactions, enhancing selectivity for aromatic, planar, and polarizable compounds. Compared to C18 phases, the phenyl modification provides an orthogonal retention mechanism ideal for resolving structurally related analytes and aromatic isomers. By combining moderate hydrophobic retention with π–π interaction, this phase offers versatile selectivity for method development and focused reversed-phase applications.
Reprospher 100 Phenyl from Dr. Maisch HPLC GmbH offers targeted aromatic selectivity and robust reversed-phase performance – ideal for resolving complex mixtures involving planar and aromatic analytes.
Phenyl bonded reversed-phase phase – USP L11 classification
Fully porous silica with 100 Å pore size
π–π interaction for enhanced separation of aromatic compounds
Orthogonal selectivity to C18 and C8 phases
Available from 1.8 µm to 10 µm particle sizes
Aromatic drugs, natural products, and isomeric compounds
Polar and π-conjugated analytes in pharmaceutical and environmental analysis
Method development requiring alternative selectivity profiles
Retention tuning for compounds with weak interaction on C18 phases
| Particle Sizes |
|
|---|---|
| Pore Size | 100 Å |
| Surface Area | 350 m²/g |
| Phase/Modification | Phenyl |
| Particle Type | |
| Separation Mode | |
| USP Code | |
| Endcapping | Yes |
| Carbonload | 9 % |
| pH Range | 2 to 8 |
| Phase | Material Number |
|---|---|
| Reprospher 100 Phenyl, 1.8 µm | rs118.pde. |
| Reprospher 100 Phenyl, 2 µm | rs12.pde. |
| Reprospher 100 Phenyl, 2.5 µm | rs125.pde. |
| Reprospher 100 Phenyl, 3 µm | rs13.pde. |
| Reprospher 100 Phenyl, 3.5 µm | rs135.pde. |
| Reprospher 100 Phenyl, 4 µm | rs14.pde. |
| Reprospher 100 Phenyl, 5 µm | rs15.pde. |
| Reprospher 100 Phenyl, 10 µm | rs10.pde. |