Reprospher Acidosil-S is an HPLC column from Dr. Maisch HPLC GmbH, packed with ultra-pure, fully porous spherical silica functionalized with sulfonic acid (–SO₃H) groups. This modification provides strong cation exchange (SCX) properties, enabling powerful and selective retention of basic and positively charged analytes through robust ionic interactions.The sulfonic acid groups ensure high ion-exchange capacity and pH stability, making Reprospher Acidosil-S particularly suitable for the analysis of amines, alkaloids, peptides, and cationic metabolites in both pharmaceutical and bioanalytical workflows.
Reprospher Acidosil-S from Dr. Maisch HPLC GmbH offers robust SCX performance with high capacity – the ideal solution for cation-exchange chromatography of strongly basic analytes.
Strong cation exchange phase with sulfonic acid (–SO₃H) groups – USP L9
High capacity and strong retention of basic/cationic analytes
Fully porous, high-purity spherical silica for reliable performance
Suitable for aqueous buffer systems and ion-exchange LC
Manufactured and QC-tested by Dr. Maisch HPLC GmbH
Available in 5 µm and 10 µm particle sizes
SCX separations of amines, alkaloids, and basic drugs
Retention and analysis of peptides and small biomolecules
Bioanalytical workflows with cationic metabolites
Pharmaceutical QC and method development requiring strong ionic selectivity
| Particle Sizes |
|
|---|---|
| Pore Size | 100 Å |
| Surface Area | 350 m²/g |
| Phase/Modification | SO3H |
| Particle Type | |
| Separation Mode | |
| Endcapping | No |
| Carbonload | 13 % |
| pH Range | 2 to 8 |
| Phase | Material Number |
|---|---|
| Reprospher Acidosil-S, 5 µm | rs15.sh. |
| Reprospher Acidosil-S, 10 µm | rs10.sh. |