Reprospher HILIC-A is an HILIC (Hydrophilic Interaction Liquid Chromatography) column from Dr. Maisch HPLC GmbH, based on ultra-pure, fully porous spherical silica specifically tailored for the retention and separation of acidic and negatively charged analytes. Its specialized surface chemistry provides strong hydrophilic interactions and enhanced selectivity for carboxylic acids, organic acids, and other polar acidic compounds. By combining robust silica with optimized HILIC functionality, Reprospher HILICA-A ensures sharp peak shapes, reproducible retention, and compatibility with high-organic eluents typically used in HILIC, making it highly suitable for LC-MS workflows and bioanalytical applications.
Reprospher HILICA-A from Dr. Maisch HPLC GmbH offers reliable and selective HILIC performance – the ideal solution for laboratories focusing on acidic and polar analytes in high-organic chromatography systems.
HILIC stationary phase optimized for acidic analytes
Strong retention of organic acids, metabolites, and polar molecules
Fully porous, high-purity spherical silica
Compatible with high-organic mobile phases (acetonitrile-rich)
Manufactured and QC-controlled by Dr. Maisch HPLC GmbH
Available in 3 µm, 5 µm, and 10 µm particle sizes
Separation of carboxylic acids and organic acids
HILIC LC-MS of acidic metabolites and bioanalytes
Analysis of small polar molecules in pharmaceutical and metabolomics studies
Method development requiring strong retention of acidic compounds
| Particle Sizes |
|
|---|---|
| Pore Size | 100 Å |
| Surface Area | 350 m²/g |
| Particle Type | |
| Separation Mode | |
| Endcapping | No |
| Carbonload | 9 % |
| pH Range | 2 to 8 |
| Phase | Material Number |
|---|---|
| Reprospher HILIC-A, 3 µm | rs13.HCA. |
| Reprospher HILIC-A, 5 µm | rs15.HCA. |
| Reprospher HILIC-A, 10 µm | rs10.HCA. |