Reprospher 200 SAX

Wide-Pore Strong Anion Exchange Column for Acidic and Negatively Charged Analytes

Reprospher 200 SAX is a strong anion exchange (SAX) column from Dr. Maisch HPLC GmbH, based on high-purity, fully porous silica with a 200 Å pore size and functionalized with quaternary ammonium groups. The wide-pore design allows efficient mass transfer and accessibility for large or structurally complex analytes such as nucleotides, organic acids, and acidic biomolecules. Thanks to its strong ion-exchange capacity and selectivity for negatively charged species, this phase is especially well suited for pharmaceutical, environmental, and biochemical applications.

This SAX phase with wide-pore support from Dr. Maisch HPLC GmbH delivers robust ion-exchange performance and high resolution – ideal for demanding separations of negatively charged molecules in HPLC.

Key Features:

  • Quaternary ammonium bonded SAX phase – USP L14 classification

  • Fully porous, high-purity silica with 200 Å pore size

  • High retention for strongly acidic and anionic compounds

  • Stable performance in ion-exchange and salt-gradient applications

  • Available from 3 µm to 50 µm particle sizes

Typical Applications:

  • Organic acids, nucleotides, and phosphorylated compounds

  • Ion-exchange separations in pharmaceutical QC and bioanalysis

  • LC methods requiring strong retention of anionic species

  • Preparative or semi-preparative workflows with acidic analytes

Specifications

Request Product
Particle Sizes
  • 3 µm
  • 5 µm
  • 10 µm
  • 30 µm
  • 50 µm
Pore Size 200 Å
Surface Area 160 m²/g
Phase/Modification SAX
Particle Type
Separation Mode
Endcapping No
Carbonload 7 %
pH Range 2 to 8

Material Numbers

Phase Material Number
Reprospher 200 SAX, 3 µm rs23.sax.
Reprospher 200 SAX, 5 µm rs25.sax.
Reprospher 200 SAX, 10 µm rs20.sax.
Reprospher 200 SAX, 30 µm rs230.sax.
Reprospher 200 SAX, 50 µm rs250.sax.
Reprospher 200 Phenyl Reprospher 200 Si

Any questions?
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info@dr-maisch.com +49 7073 5035 7

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