Reprospher 200 Si

Wide-Pore Bare Silica Column for Normal-Phase and Adsorption Chromatography of Large Molecules

Reprospher 200 Si is a high-purity, unmodified silica HPLC column from Dr. Maisch HPLC GmbH, featuring a fully porous silica matrix with a 200 Å pore size. The wide-pore structure and active silanol surface make this phase ideal for classical normal-phase chromatography and adsorption-based separations of larger polar compounds, such as peptides, carbohydrates, and natural products. Its stable retention behavior and high surface activity provide excellent resolution for polar analytes and allow effective method development under non-aqueous conditions.

This wide-pore bare silica phase from Dr. Maisch HPLC GmbH is the ideal choice for high-resolution normal-phase separations involving large, polar molecules and method development requiring strong surface interaction.

Key Features:

  • Bare silica phase – USP L3 classification

  • Fully porous, high-purity silica with 200 Å pore size

  • Strong polar interaction for normal-phase and dry loading applications

  • High surface activity and excellent peak shape for polar analytes

  • Available in 5 µm

Typical Applications:

  • Normal-phase chromatography of peptides and polar organics

  • Adsorption separations of natural products and glycosylated compounds

  • Sample pre-purification and dry-loading in preparative LC

  • Orthogonal selectivity to reversed-phase and HILIC methods

Specifications

Request Product
Particle Size
  • 5 µm
Pore Size 200 Å
Surface Area 160 m²/g
Phase/Modification Si
Particle Type
Separation Modes
USP Code
Endcapping No
Carbonload 0 %
pH Range 2 to 8

Material Number

Phase Material Number
Reprospher 200 Si, 5 µm rs25.00.
Reprospher 200 SAX

Any questions?
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info@dr-maisch.com +49 7073 5035 7

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