Ultrasep ES 100 Dimethyl RP18

Endcapped C18 Column for Robust Reversed-Phase HPLC

Ultrasep ES 100 Dimethyl RP18 is a silica-based HPLC column with a 100 Å pore size and a dimethyl endcapped C18 bonded phase. The combination of strong hydrophobic retention from the C18 chains and reduced silanol activity due to endcapping ensures excellent peak symmetry, particularly for basic and polar analytes.

This column provides high separation efficiency, excellent reproducibility, and robust performance, making it suitable for both routine QC tasks and method development in pharmaceutical, environmental, and food analysis.

Ultrasep ES 100 Dimethyl RP18 combines strong hydrophobic retention, endcapped stability, and reproducible performance – the reliable choice for reversed-phase HPLC separations across diverse applications.

Key Features:

  • Silica-based stationary phase with 100 Å pore size

  • Dimethyl endcapped octadecyl (C18) bonded phase – USP L1 classification

  • Strong hydrophobic retention with reduced silanol interactions

  • Excellent reproducibility, resolution, and peak symmetry

  • Suitable for basic and polar compounds

  • Available particle size: 5 µm

Typical Applications:

  • Pharmaceutical compound and impurity profiling

  • Separation of basic and polar analytes with improved peak shapes

  • Environmental and food testing under reversed-phase conditions

  • Method development requiring robust C18 selectivity

Specifications

Request Product
Particle Size
  • 5 µm
Pore Size 100 Å
Particle Type
Separation Mode
USP Code
pH Range 2 - 8

Material Number

Phase Material Number
Ultrasep ES 100 Dimethyl RP18, 5 µm u15.dm9.
Ultrasep ES 100 CN Ultrasep ES 100 Methyl-RP8

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