Ultrasep ES 100 Methyl-RP8

C8 Column with Methyl Endcapping for Balanced Reversed-Phase HPLC

Ultrasep ES 100 Methyl-RP8 is a silica-based HPLC column with a 100 Å pore size and an octyl (C8) bonded phase combined with methyl endcapping. This design delivers moderate hydrophobic retention, faster elution compared to C18, and improved peak symmetry for basic compounds due to reduced silanol activity.

The column provides robust performance, high efficiency, and excellent reproducibility, making it a reliable choice for both routine quality control and method development in reversed-phase HPLC.

Ultrasep ES 100 Methyl-RP8 combines balanced hydrophobic retention, endcapped stability, and reproducible performance – the versatile choice for efficient reversed-phase HPLC separations.

Key Features:

  • Silica-based stationary phase with 100 Å pore size

  • Octyl (C8) bonding with methyl endcapping – USP L7 classification

  • Balanced hydrophobic retention with faster elution than C18

  • Reduced silanol interactions for improved peak shapes

  • High reproducibility and separation efficiency

  • Available particle size: 7 µm

Typical Applications:

  • Pharmaceutical compound and impurity analysis

  • Environmental testing of moderately hydrophobic compounds

  • Food and beverage quality control with shorter analysis times

  • Method development requiring intermediate hydrophobic selectivity

Specifications

Request Product
Particle Size
  • 7 µm
Pore Size 100 Å
Particle Type
Separation Mode
USP Code
pH Range 2 - 8

Material Number

Phase Material Number
Ultrasep ES 100 Methyl-RP8, 7 µm u17.m8.
Ultrasep ES 100 Dimethyl RP18 Ultrasep ES 100 Methyl-RP18

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