Ultrasep ES Amid H-RP18PA

Polar-Embedded C18 Column for Enhanced Peak Symmetry and Selectivity

Ultrasep ES Amid H-RP18P is a silica-based HPLC column with a polar-embedded amidic C18 bonded phase. The embedded amide group minimizes silanol interactions, providing improved peak symmetry for basic and polar analytes, while maintaining strong hydrophobic retention from the C18 chains.

This phase offers enhanced selectivity, combining hydrophobic and polar interactions, making it particularly useful for complex mixtures, stability-indicating assays, and pharmaceutical analysis. The robust bonding ensures long lifetime, even under harsh pH and temperature conditions.

Ultrasep ES Amid H-RP18P delivers balanced hydrophobic retention, polar selectivity, and excellent robustness – the reliable choice for challenging reversed-phase HPLC separations.

Key Features:

  • Silica-based stationary phase with polar-embedded amidic C18 bonded phase

  • Combines hydrophobic retention with polar interactions

  • Improved peak shapes for basic and polar compounds

  • Robust performance under a wide pH range and high temperatures

  • Available particle size: 5 µm

Typical Applications:

  • Pharmaceutical impurity profiling and drug substance analysis

  • Stability-indicating assays and forced degradation studies

  • Complex mixture analysis requiring complementary selectivity

  • Environmental and food testing of polar and hydrophobic analytes

Specifications

Request Product
Particle Size
  • 5 µm
Pore Size 100 Å
Particle Type
Endcapping Yes
pH Range 2 - 8

Applications

Material Number

Phase Material Number
Ultrasep ES Amid H-RP18PA, 5 µm u15.ah9pa.
Ultrasep ES Amid H-RP18P Ultrasep ES Amid RP18A

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