Ultrasep ES Amid RP18A is a silica-based HPLC column with a polar-embedded amidic C18 bonded phase. The embedded amide functionality reduces residual silanol activity, resulting in sharper peak shapes and improved reproducibility, especially for basic and polar compounds. At the same time, the C18 chains provide strong hydrophobic retention, making this column highly versatile.
This phase is particularly suitable for complex mixtures and method development, where a combination of hydrophobic and polar interactions is needed. Its robust bonding chemistry ensures long column lifetime under harsh pH and temperature conditions.
Ultrasep ES Amid RP18A combines strong hydrophobic retention, polar interaction capability, and robust performance – the versatile choice for demanding reversed-phase HPLC separations.
Silica-based stationary phase with polar-embedded amidic C18 bonded phase
Strong hydrophobic retention with additional polar selectivity
Reduced silanol interactions for improved peak symmetry
Excellent reproducibility and robustness under demanding conditions
Available particle size: 5 µm
Pharmaceutical impurity profiling and drug substance analysis
Separation of polar and basic analytes with improved peak symmetry
Stability-indicating assays under harsh analytical conditions
Food, environmental, and chemical testing with complex matrices
| Particle Size |
|
|---|---|
| Pore Size | 100 Å |
| Particle Type | |
| pH Range | 2 - 8 |
| Phase | Material Number |
|---|---|
| Ultrasep ES Amid RP18A, 5 µm | u15.a9a. |