Ultrasep ES Amid RP18AM is a silica-based HPLC column with a polar-embedded amidic C18 bonded phase. The embedded amide functionality provides additional polar selectivity while reducing silanol interactions, which results in sharper peak shapes for basic and polar analytes. At the same time, the C18 chains ensure strong hydrophobic retention, making this phase highly versatile.
This combination of hydrophobic and polar interaction mechanisms makes RP18AM ideal for complex separations, stability-indicating assays, and pharmaceutical impurity profiling. Its robust bonding chemistry provides long lifetime and reproducible results even under aggressive pH and temperature conditions.
Ultrasep ES Amid RP18AM delivers balanced hydrophobic and polar selectivity with high robustness – the reliable choice for challenging reversed-phase HPLC separations.
Silica-based stationary phase with polar-embedded amidic C18 bonding
Combines strong hydrophobic retention with polar interactions
Reduced silanol activity for improved peak symmetry
High robustness under demanding pH and temperature conditions
Available particle size: 5 µm
Separation of polar and basic pharmaceuticals
Stability-indicating assays and forced degradation studies
Complex mixture analysis in food, environmental, and chemical testing
Method development requiring orthogonal selectivity
| Particle Size |
|
|---|---|
| Pore Size | 100 Å |
| Particle Type | |
| pH Range | 2 - 8 |
| Phase | Material Number |
|---|---|
| Ultrasep ES Amid RP18AM, 5 µm | u17.a9am. |