VisionHT C18 Polar is a silica-based HPLC column with a polar-embedded C18 bonded phase, designed to combine strong hydrophobic retention with additional polar selectivity. The embedded polar group reduces silanol interactions, resulting in sharper peak shapes and improved reproducibility, particularly for basic and polar analytes.
This dual retention mechanism makes VisionHT C18 Polar highly versatile for complex separations, stability-indicating assays, and pharmaceutical impurity profiling. With multiple particle size options, it is suitable for both high-efficiency separations and routine quality control.
VisionHT C18 Polar delivers balanced hydrophobic and polar selectivity with robustness – the reliable choice for laboratories facing challenging reversed-phase HPLC separations.
Silica-based stationary phase with polar-embedded C18 chemistry
Combines strong hydrophobic retention with polar interactions
Reduced silanol activity for improved peak symmetry
Robust bonding ensures reproducibility and long column lifetime
Available particle sizes: 1.5 µm, 3 µm, 5 µm, 10 µm
Separation of polar and basic pharmaceuticals
Stability-indicating assays and forced degradation studies
Complex mixture analysis in food, environmental, and chemical testing
Method development requiring orthogonal selectivity
| Particle Sizes |
|
|---|---|
| Pore Size | 100 Å |
| Phase/Modification | C18 |
| Particle Type | |
| Separation Modes | |
| USP Code | |
| pH Range | 2 - 8 |
| Phase | Material Number |
|---|---|
| VisionHT C18 Polar, 1.5 µm | 5211037 |
| VisionHT C18 Polar, 3 µm | 5211038 |
| VisionHT C18 Polar, 5 µm | 5211039 |
| VisionHT C18 Polar, 10 µm | 5211040 |