VisionHT HILIC

Hydrophilic Interaction HPLC Column for Polar Compound Analysis

VisionHT HILIC is a silica-based HPLC column with hydrophilic interaction liquid chromatography (HILIC) functionality, designed for the separation of highly polar and hydrophilic analytes. The HILIC bonded phase provides strong retention for compounds that are poorly retained on conventional reversed-phase columns, delivering sharp peak shapes and reproducibility for polar separations.

With multiple particle size options, VisionHT HILIC offers flexibility for high-efficiency separations as well as routine analytical workflows. It is particularly well-suited for pharmaceutical, biochemical, and environmental applications where hydrophilic and ionic compounds need to be analyzed with high accuracy.

VisionHT HILIC provides reliable retention and reproducibility for polar compounds – the dependable choice for laboratories requiring robust HILIC separations.

Key Features:

  • Silica-based stationary phase with HILIC functionality

  • Strong retention of highly polar and hydrophilic analytes

  • Enhanced reproducibility and sharp peak shapes

  • Robust bonding ensures long column lifetime

  • Available particle sizes: 1.5 µm, 3 µm, 5 µm, 10 µm

Typical Applications:

  • Pharmaceutical analysis of polar drugs and metabolites

  • Biochemical testing of amino acids, nucleotides, and carbohydrates

  • Environmental monitoring of hydrophilic contaminants

  • Method development requiring orthogonal selectivity to reversed-phase HPLC

Specifications

Request Product
Particle Sizes
  • 1.5 µm
  • 3 µm
  • 5 µm
  • 10 µm
Pore Size 120 Å
Particle Type
Separation Modes
pH Range 2 - 8

Applications

HPLC Method for Melamine
5 µm (250 x 4.6 mm)
0 min20 min
Melamine - ELSD Method
5 µm (250 x 4.6 mm)
Melamine from Biscuit
5 µm (250 x 4.6 mm)
Melamine standardSpiked pork before SPESpiked pork after SPE0 min14 min
Melamine from Pork
5 µm (250 x 4.6 mm)
UHPLCHPLC0 min20 min
Melamine - HPLC Method Transfer to UHPLC
µm ( x mm)
0 min5 min
UHPLC Method for Malamine
1.5 µm (50 x 2 mm)

Material Numbers

Phase Material Number
VisionHT HILIC, 1.5 µm 5211044
VisionHT HILIC, 3 µm 5211045
VisionHT HILIC, 5 µm 5211046
VisionHT HILIC, 10 µm 5211047
VisionHT C18 Polar VisionHT Silica

Any questions?
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info@dr-maisch.com +49 7073 5035 7

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