Adsorbosphere XL Si is a high-purity, unbonded silica phase designed for normal-phase and adsorption chromatography and offers improved stability and column life. With its unmodified silanol-rich surface, this column provides strong polar retention mechanisms such as hydrogen bonding and dipole interactions — ideal for separating isomers, neutral compounds, and polar organics.
Unlike conventional bare silica, the surface treatment increases mechanical durability and minimizes baseline noise, making Adsorbosphere XL Si a robust option for both method development and routine applications.
Adsorbosphere XL Si combines classical silica selectivity with enhanced durability — built for labs using normal-phase methods under demanding conditions.
Pure, unmodified silica (USP L3)
Strong polar interactions for normal-phase and adsorption separations
High surface activity for retention of polar and isomeric compounds
Suitable for non-polar solvents (e.g. hexane, heptane, ethyl acetate)
Excellent column lifetime, available in 3 µm, 5 µm and 10 µm particle sizes
Reproducible performance in normal-phase workflows
Classical normal-phase separations (e.g. lipids, alkaloids, plant extracts)
Structural and positional isomer resolution
Dry-loading and preparative setups
Polar compound separation using non-aqueous mobile phases
Method development in NP and adsorption chromatography
| Particle Sizes |
|
|---|---|
| Pore Size | 100 Å |
| Surface Area | 200 m²/g |
| Phase/Modification | Si |
| Particle Type | |
| Separation Modes | |
| USP Code | |
| Endcapping | No |
| Carbonload | 0 % |
| Phase | Material Number |
|---|---|
| Adsorbosphere XL Si, 3 µm | 5200070 |
| Adsorbosphere XL Si, 5 µm | 5200071 |
| Adsorbosphere XL Si, 10 µm | 5200072 |