Exsil 100 ODS is an octadecyl-modified (C18) silica-based HPLC stationary phase based on high-purity Exsil 100 silica with a nominal pore size of 100 Å. The ODS bonded ligand provides strong hydrophobic interactions, enabling high retention and excellent resolution for a wide range of small to medium molecular weight compounds.
The C18 surface chemistry makes Exsil 100 ODS a general-purpose reversed-phase HPLC material suitable for routine analysis as well as method development. The phase delivers high chromatographic efficiency, good peak symmetry, and reproducible retention behavior across a broad range of mobile phase compositions.
Controlled silica synthesis and stable ODS bonding ensure excellent batch-to-batch reproducibility and robust chromatographic performance, making Exsil 100 ODS a reliable choice for everyday reversed-phase separations.
Exsil 100 ODS offers robust performance, high efficiency, and reliable selectivity, making it a proven reversed-phase standard for small-molecule HPLC separations.
• Octadecyl (C18, ODS) modified silica-based HPLC phase
• 100 Å pore size optimized for small and medium molecular weight analytes
• Strong hydrophobic retention for reversed-phase HPLC
• High chromatographic efficiency and good peak shape
• Broad applicability as a general-purpose C18 phase
• Reproducible retention and stable selectivity
• High batch-to-batch reproducibility
• Suitable for analytical and preparative HPLC
• Particle sizes available in: 3 µm, 5 µm, 7 µm, 10 µm
• Reversed-phase HPLC of pharmaceutical APIs and intermediates
• Separation of small and medium-sized organic molecules
• Method development and routine QC applications
• Analysis of compounds with moderate to high hydrophobicity
• Routine separations in pharmaceutical, chemical, and analytical laboratories
| Particle Sizes |
|
|---|---|
| Pore Size | 100 Å |
| Surface Area | 200 m²/g |
| Phase/Modification | C18 |
| Particle Type | |
| Separation Mode | |
| USP Code | |
| Endcapping | Yes |
| Carbonload | 10 % |
| pH Range | 2 to 8 |
| Phase | Material Number |
|---|---|
| Exsil 100 ODS, 3 µm | 5136515. |
| Exsil 100 ODS, 5 µm | 5136528. |
| Exsil 100 ODS, 7 µm | 5136539. |
| Exsil 100 ODS, 10 µm | 5136544. |