Exsil 100 SAX is a strong anion-exchange (SAX) HPLC stationary phase based on high-purity Exsil 100 silica with a nominal pore size of 100 Å. The permanently charged quaternary ammonium functionality provides strong electrostatic interactions, enabling efficient and reproducible retention of negatively charged analytes across a wide pH range.
The strong anion-exchange surface chemistry makes Exsil 100 SAX particularly suitable for ion-exchange chromatography of small to medium molecular weight acidic compounds. The phase delivers high retention strength, stable selectivity, and reliable performance under demanding mobile phase conditions, making it suitable for both routine analysis and method development.
Controlled silica synthesis and robust surface modification ensure excellent batch-to-batch reproducibility, consistent chromatographic behavior, and long-term stability.
Exsil 100 SAX offers strong and reproducible anion-exchange selectivity combined with robust performance, making it a reliable choice for ion-exchange HPLC separations of negatively charged small molecules.
• Strong anion-exchange (SAX) silica-based HPLC phase
• 100 Å pore size optimized for small and medium molecular weight analytes
• Permanently charged quaternary ammonium functionality
• Strong and stable anion-exchange retention mechanism
• High selectivity for acidic and anionic compounds
• Reproducible retention behavior across a wide pH range
• High batch-to-batch reproducibility
• Suitable for analytical and preparative ion-exchange HPLC
• Particle sizes available in: 5 µm, 10 µm
• Ion-exchange HPLC of acidic and anionic compounds
• Separation of organic acids and acidic metabolites
• Analysis of ionic pharmaceutical intermediates
• Method development for strong anion-exchange separations
• Routine QC in pharmaceutical, chemical, and analytical laboratories
| Particle Sizes |
|
|---|---|
| Pore Size | 100 Å |
| Surface Area | 200 m²/g |
| Phase/Modification | SAX |
| Particle Type | |
| Separation Mode | |
| USP Code | |
| Endcapping | No |
| Phase | Material Number |
|---|---|
| Exsil 100 SAX, 5 µm | 5136529. |
| Exsil 100 SAX, 10 µm | 5136545. |