Exsil 80 Hexyl is a silica-based HPLC stationary phase with an 80 Å pore size and a hexyl (C6) bonded surface, designed for intermediate hydrophobic retention in reversed-phase HPLC. Positioned between short-chain phases (C1, C4) and longer alkyl phases (C8, C18), the C6 modification provides balanced retention strength and distinct selectivity for small-molecule separations.
The controlled pore structure and high surface area support high chromatographic efficiency, sharp peak shapes, and reproducible retention behavior. Exsil 80 Hexyl is particularly useful for compounds that elute too quickly on short-chain phases or too strongly on C8 or C18 columns.
Exsil 80 Hexyl delivers controlled intermediate retention, high efficiency, and reliable reproducibility, making it an effective choice for fine-tuned reversed-phase HPLC separations of small molecules.
Silica-based HPLC stationary phase with 80 Å pore size
Hexyl (C6) bonded phase for intermediate hydrophobic retention
Balanced selectivity between C4 and C8 phases
High efficiency and reproducible chromatographic performance
Optimized for small-molecule reversed-phase HPLC
Available particle sizes: 3 µm, 5 µm, 10 µm
Reversed-phase separation of moderately hydrophobic compounds
Pharmaceutical analysis of small molecules and intermediates
Method development requiring fine-tuned retention strength
Faster HPLC methods compared to C8 or C18
Food, environmental, and chemical analysis
| Particle Sizes |
|
|---|---|
| Pore Size | 80 Å |
| Surface Area | 220 m²/g |
| Phase/Modification | C6 |
| Particle Type | |
| Separation Mode | |
| USP Code |
| Phase | Material Number |
|---|---|
| Exsil 80 Hexyl, 3 µm | 5136483. |
| Exsil 80 Hexyl, 5 µm | 5136491. |
| Exsil 80 Hexyl, 10 µm | 6136976. |