Exsil 80 Nitrile is a silica-based HPLC stationary phase with an 80 Å pore size and a nitrile (cyano, CN) bonded surface, offering distinct polar selectivity and versatile chromatographic behavior. The CN functionality enables operation in both reversed-phase and normal-phase modes, providing orthogonal selectivity compared to alkyl-bonded phases.
The controlled pore structure delivers a high surface area, supporting sharp peak shapes, high efficiency, and reproducible retention for small-molecule separations. Exsil 80 Nitrile is particularly useful for analytes that require moderate polarity-based interactions or alternative selectivity to C8 and C18 phases.
Exsil 80 Nitrile provides versatile polarity-based selectivity, high efficiency, and reliable performance, making it a practical choice for flexible small-molecule HPLC separations.
Silica-based HPLC stationary phase with 80 Å pore size
Nitrile (CN) bonded phase for polar and dipolar interactions
Suitable for reversed-phase and normal-phase chromatography
Orthogonal selectivity to alkyl-bonded phases
High efficiency and reproducible chromatographic performance
Available particle sizes: 3 µm, 5 µm, 10 µm
Separation of polar and moderately non-polar small molecules
Normal-phase HPLC of organic compounds and intermediates
Reversed-phase methods requiring alternative selectivity
Pharmaceutical, chemical, food, and environmental analysis
Method development using orthogonal stationary phases
| Particle Sizes |
|
|---|---|
| Pore Size | 80 Å |
| Surface Area | 220 m²/g |
| Phase/Modification | CN |
| Particle Type | |
| Separation Modes | |
| USP Code |
| Phase | Material Number |
|---|---|
| Exsil 80 Nitrile, 3 µm | 5136480. |
| Exsil 80 Nitrile, 5 µm | 5136489. |
| Exsil 80 Nitrile, 10 µm | 5136502. |